Systolic Anterior Motion of the Mitral Valve: In Vitro Flow Studies

by Xavier P. Lefebvre, Georgia Tech, Atlanta, United States,
Shengqiu He, Georgia Tech, Atlanta, United States,
Robert A. Levine, Georgia Tech, Atlanta, United States,
Ajit P. Yoganathan, Georgia Tech, Atlanta, United States,



Document Type: Proceeding Paper

Part of: Engineering Mechanics

Abstract:

Using an in-vitro approach, the goal of this study was to determine and to characterize the mechanism of systolic anterior motion of the mitral valve in obstructive hypertrophic cardiomyopathy. It was found that the abnormal motion of the mitral valve is caused by changes in the geometry of the mitral apparatus which affected both the mitral leaflets and the ventricular flow field.

Subject Headings: Valves | Motion (dynamics) | Fluid flow | Geometrics | Fluid mechanics | Field tests | Biological processes

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