Optimal Design of Aortic Leaflet Prosthesis

by Dhanjoo N. Ghista, Biomedical Research Division, NASA, Ames Research Center, Moffett Field, Calif.,
K. B. Chandran, Research Assoc.; Biomechanics Lab., Tulane Medical School, New Orleans, La.,
Gautam Ray, Asst. Prof.; Dept. of Mech. Engrg., Southern Univ., Baton Rouge, La.,
Helmut Reul, Helmholtz Inst. an der RWTH Aachen Goethestr., Aachen, West Germany,


Serial Information: Journal of the Engineering Mechanics Division, 1978, Vol. 104, Issue 1, Pg. 97-117


Document Type: Journal Paper

Discussion: Gould Phillip L. (See full record)
Closure: (See full record)

Abstract: The design criteria for an optimum prosthetic-aortic leaflet valve are a smooth washout in the valve cusps, minimal leaflet stress, minimal transmembrane pressure for the valve to open, an adequate lifetime (for a given blood-compatible leaflet material's fatigue data). A rigorous design analysis is presented to obtain the prosthetic tri-leaflet aortic valve leaflet's optimum design parameters. Four alternative optimum leaflet geometries are obtained to satisfy the criteria of a smooth washout and minimal leaflet stress. The leaflet thicknesses of these four optimum designs are determined by satisfying the two remaining design criteria for minimal transmembrane opening pressure and adequate fatigue lifetime, which are formulated in terms of the elastic and fatigue properties of the selected leaflet material - Avcothane-51 (of the Avco-Everett Co. of Massachusetts). Prosthetic valves are fabricated on the basis of the optimum analysis and the resulting detailed engineering drawings of the designs are also presented in the paper.

Subject Headings: Valves | Fatigue (material) | Plastic design | Elastic analysis | Geometrics | Parameters (statistics) | Thickness | North America | Massachusetts | United States

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