Photodynamic Inactivation of Infectious Agents

by M. Floyd Hobbs, (M.ASCE), Sr. Chemist; Environmental Engrg. Lab., FMC Corp., Santa Clara, Calif.,
Jean S. Lennon, Chemist; Central Engrg. Labs., FMC Corp., Santa Clara, Calif.,
Joseph L. Melnick, Prof. and Chmn.; Dept. of Virology and Epidemiology, Baylor Coll. of Medicine, Houston, Tex.,
Craig Wallis, Prof.; Dept. of Virology and Epidemiology, Baylor Coll. of Medicine, Houston, Tex.,
Charles P. Gerba, Asst. Prof.; Dept. of Virology and Epidemiology, Baylor Coll. of Medicine, Houston, Tex.,


Serial Information: Journal of the Environmental Engineering Division, 1977, Vol. 103, Issue 3, Pg. 459-472


Document Type: Journal Paper

Abstract: The photodynamic inactivation of poliovirus by use of the photoreactive dye methylene blue at pH 10 and monochromatic lights was investigated on a continuous flow basis. The photodynamic inactivation process was effective for virus inactivation in clarified wastewater and requires various unit operations that are inherent to both the tertiary treatment of secondary effluent for phosphorus and ammonia removal and for the physical-chemical treatment of sewage. The process can be used in existing physical-chemical waste treatment plants, secondary waste treatment plants where tertiary treatment for nutrient and improved carbon removals are of concern, and water treatment plants where the lime-softening process is used for water purification. Photodynamic inactivation rates for poliovirus using methylene blue at pH 10 were sensitive to heat during sensitization and subsequent irradiation.

Subject Headings: Water treatment plants | Waste treatment plants | Chemical treatment | Industrial wastes | pH | Recycling | Dyes | Viruses

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